69.The treatment of eczema, the synonym for dermatitis-4

Eczema is an inflammatory condition of the skin, the cause of which may be from outside environment, immune system, or a combination of both. Systemic therapy is considered to be effective immediately. The doctors and patients need to concern the potential side effect. Of course, the serious situation and secondary infection are still needed.

Calcineurin Antagonists

Calcineurin antagonists induce T-cell suppression. It is applied not only in organ transplant, but also in topical use for eczema in skin. Tacrolimus is the oral medication of the treatment. Why do you need to suppress T-cell? This is because the body produces white blood cells called lymphocytes (T-cell) to fight infection or foreign substances which have entered the body. The immune system of the body recognizes the new tissue which likes organ transplant or graft as 'foreign' to you. Then the immune system will try to attack it with certain lymphocytes. Tacrolimus works by preventing the production of these lymphocytes and this helps prevent rejection of the transplanted tissue. The common side effects are a burning sensation and itching. So use of these agents will need to have appropriate information and control mechanisms for patients.

Antiseptics and Antibiotics

Astringents have good antibacterial activity such as potassium permanganate. It usually contains triclosan or chlorhexidine is part of therapeutic tradition, although there are environmental and irritancy issues concerns.

Use of topical antibiotics is not favored. This is because sensitization can often occur. Otherwise, the other general concern is it has consequences for the usefulness of antibiotics in more serious situations of systemic infection. But systemic antibiotic therapy can be necessary for erysipelas or other serious skin infections.

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