80.Restricted ingredients in cosmetic and skin care products

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Restricted ingredients in cosmetic and skin care products by regulation. Ingredient Potential toxicity Hexachlorophene Neurotoxic effects Ability to penetrate human skin Mercury compounds Accumulation in the body Skin irritation Allergic reactions Neurotoxicity Bithionol Photocontact sensitization Halogenated salicylanilides Photocontact sensitization Chlorofluorocarbon propellants Hazardous to human health Chloroform Plausible carcinogenicity Vinyl chloride Plausible carcinogenicity Zirconium-containing complexes Lung toxicity Methylene chloride Plausible carcinogenicity help to find the specific skincare product ingredients by "skin+" App.

20-.Why do you have gray hairs?

Why do you have gray hairs?

gray hairs



The reasons that cause gray hairs
l   oxidative stress
 Inappropriate production of oxidants will intricately connect to ageing and life
Span such as the cell in hairs
l   Lack of melanocyte in keratinocytes.
Melanocyte can not excrete melanin

The chemical properties of hairs
l   The main component is keratin included eighteen amino acids.
l   Hairs contain 12-13% water (250c, RH65%)
l   Hair has Melanocyte to excrete melanin and dominates 3%.
l   Hair has lipids and depends on individuals. Most of all are free fatty acids and dominate around 1-9%.
l   Hairs have trace elements such as Cu, Zn, Ma, Ca, Mn, P, and Si.

The physical properties of hairs
The hair has cysteine, so hair is strong and also has extension.

Amino acid
Keratinocyte of hair(%)
Keratinocyte of epidermis(%)
Glycine
6
6
Alanine
2.8
Valine
5.5
4.2
Leucine
6.4
8.3
Isoleucine
4.8
6.8
Phenylalanine
2.4-3.6
2.8
Proline
4.3
3.2
Serine
7.4-10.6
16.5
Threonine
7.0-8.5
3.4
Tyrosine
2.2-3.0
3.4-5.7
Aspartate
3.9-7.7
6.4-8.1
Glutamate
13.6-14.2
9.1-15.4
Arginine
8.9-10.8
5.9-11.7
Lysine
1.9-3.1
3.1-6.9
Histidine
0.6-1.2
0.6-1.8
Tryptophan
0.4-1.3
0.5-1.8
Cystine
16.6-18
2.3-3.8
Methionine
0.7-1.0
1.0-2.5

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