GlamX_blog

Daily skin cleaning Skin cleansing with soaps and detergents cause barrier damage in epidermis. The surfactants in modern cleansing products are anionics, nonionics, and  amphoterics. The dermatological effects of surfactants on skin can be attributed to four fundamental mechanisms (1) adsorption to skin surface, (2) removal of skin components, (3) penetration into deeper skin layers, and (4) cytotoxic effects on living cells in the epidermis. They will affect barrier homeostasis of the skin and other physiological factors. Shortly after the application of surfactants, a Stratum corneum swelling occurs. Long-term application of surfactants, dehydration of the Stratum corneum occurs. They are derived lipids into lamellar bilayers are disrupted . The washing procedure is of particular importance for barrier lipids, barrier function, and Stratum corneum water content. Sensitive skin is considered a special condition in which there is reduced tolerance and high incidences of...

There are many factors that cause skin damage. How does the damage result? They may be from the UV light, pollution , and so on. For example, photoaging and free radical. Then the cells are influenced.   photoaging Sunlight will cause phtoaging. Chronically irradiated skin is metabolically hyperactive, thus giving rise to epidermal hyperplasia and neoplasia , increased production of elastic fibers (solar elastosis), accelerated breakdown and synthesis of collagen , and enhanced inflammatory processes. If DNA damaged and a mutation occurs in the gene, the keratinocytes may lose their ability. Free radical and antioxidants Stratum corneum is frequently and directly exposed not only to UVR but also to other outside forces such as air pollutants, chemical oxidants, smoking, and microorganisms . They are the resources of free radicals . If the protection is insufficient, oxidative damage may occur . Then the chronic accumulation of such deviated cell components may result i...

Eczema is an inflammatory condition of the skin , the cause of which may be from outside environment, immune system, or a combination of both. Systemic therapy is considered to be effective immediately. The doctors and patients need to concern the potential side effect. Of course, the serious situation and secondary infection are still needed. Calcineurin Antagonists Calcineurin antagonists induce T-cell suppression . It is applied not only in organ transplant, but also in topical use for eczema in skin. T acrolimus is the oral medication of the treatment. Why do you need to suppress T-cell? This is because the body produces white blood cells called lymphocytes (T-cell) to fight infection or foreign substances which have entered the body. The immune system of the body recognizes the new tissue which likes organ transplant or graft as 'foreign' to you. Then the immune system will try to attack it with certain lymphocytes. Tacrolimus works by preventing the producti...

Eczema is an inflammatory condition of the skin, the cause of which may be from outside environment, immune system, or a combination of both . The patients and the treating doctor hope the effective and convenient dermatological therapy. Physical therapy is usually inconvenient and need to a lot of patient but is effective. Systemic therapy is considered to be effective immediately. The patient and the treating doctor are often being conservative due to the risk of potential side effect. The following is dermatological therapies. Topical Corticosteroids Topical corticosteroids are certainly the mainstay of dermatological treatment of  inflammatory conditions. Corticosteroids function via by inducing suppression of inflammatory cytokines and inhibiting function of T cells and a range of other inflammatory cells. The production of arachidonic acid which is one of the fatty acid in skin is affected as well as the function of vascular and connective tissues. The pot...

Eczema is an inflammatory condition of the skin, the cause of which may be from outside environment, immune system, or a combination of both. The basic symptom is itch. Spreading emollients is one of way to prevent the itchy skin.   Emollients Emollients can keep the skin dry by reducing water loss from the epidermis. Emollients are an essential part of their daily skin care for patients with dry skin such as eczema. There are many types of products like ointments , creams, lotions and so on. Evaporation of the product’s water from the skin can ease itching. It is important to avoid products containing potential allergens. Emollients can prevent eczema by maintaining skin barrier function An emollient is a   humectant,   lubricant   and   occluder. Occlusion provides a layer of oil on the skin's surface, thus slowing down water loss. A humectant enhances the surface of the skin's capacity to hold water. A lubricant reduces friction when ...

Eczema is an inflammatory condition of the skin, the cause of which may be from outside environment, immune system, or a combination of both. The basic symptom is itch. There are many period of the symptoms for eczema. The conditions also could be acute, subacute, or chronic. The judgement could be by the careful histological examination from epidermis and dermis to observe the cell infiltrates. The dermal stroma contains all the necessary components for amplification and modification of the cellular response. The response includes the separation of the keratinocytes in stratum corneum in epidermis. The following is dermatological therapies.  part1 Bathing and Soaks There are three functions of bathing and soaks. 1.       Relief from itch for a moment. 2.       Astringent properties on skin which is exudative 3.       Prevent the bacterial proliferation such as Staphylococcus aur...

How do pimples, zits, acne, blackhead and whitehead appear?  There are two kinds of sebaceous glands. One connects the follicle , and the other links the skin surface directly.     The frequent distributions of sebaceous gland are in forehead, cheek, chin, back, center of chest, and armpit. If the oil secretion is seriously flourished , it sticks out from the skin and causes pimples , zits and acne. As the sebum touch the air, it oxidizes and turns into black color . That is blackhead . The whitehead is oil secretion seriously flourished. But it can’t excrete out of the skin, it starts to block in the sebaceous gland and stretches the gland space . If the space has bacteria , it would become inflamed pimple and fill with pus .  -------------------------------------------------------------------------------------------------- help to find the specific skincare product ingredients by "skin+" App

Why do we get old? The genes are the important rue of aging. How do they do? Why do human age? Some elders are still healthy, but some are weak and sick. The scientists do not come to the definitive conclusions yet. There are some aging theories as the following.    The aging theories _part5 Genetic Endowment A set of genes determine your congenital disease, life expectancy, many degenerative diseases, etc. Gene has two copies, and one inherited from each parent. So gene is the essential factor of age. Telomere’s length Telomere is the end of a chromosome which protects the end of the chromosome from deterioration and fusion with the other chromosome. The length of telomere will be shorter as cell division each time . If the length of telomere is shorter than a significant length, it will lose its protecting function for chromosome. Cell division will be  no more, and the cells age and die.  Longevity gene The scientists discover DAF-2 gene will cause cel...

Why do we get old? What are the mitochondrial damage and free radical damage? Why do human age? Some elders are still healthy, but some are weak and sick. The scientists do not come to the definitive conclusions yet. There are some aging theories as the following.    The aging theories_part4 Mitochondrial damage Mitochondrial DNA converts chemical energy from food into cells. It maintains our daily life and repairs the damaged cells. As time goes by, mitochondrial DNA will be damaged such as the influence of environment , binge eating , etc. But it will not be so easy to repair as young age .Then the body will be out of the frying pan and into the fire. Free radical damage A free radical is any atom or molecule that has a single unpaired electron in an outer shell. The  free radical is unstable , and it will tend to catch an electron from the other atom or molecule. When it catches an electron, it will affect the function of the original tissue o...

Why do we get old? Why the sweet tooth should be careful about their health? Why do human age? Some elders are still healthy, but some are weak and sick. The scientists do not come to the definitive conclusions yet. There are some aging theories as the following.  The aging theories_part3 Molecular cross linkage Cross-linking theory is from the idea of chemical change which means bond two different parts together. About food, caramelization is overheating the sugar molecules such like toast and causing the sugar molecules attached to the protein molecules . If the reaction happens to the human body, it is called glycation . This process would cause aging in specific tissues after inappropriate attachment and accumulations . The reaction will cause the tissues to become stiffer and don’t function efficiently . For example, the arteries hardens will increase risk of heart attack and stroke. The protein collagen in dermis in skin will lose the elasticity, and this ...

Why do we get old? Is there any method to slow down aging? Why do human age?  Some elders are still healthy, but some are weak and sick. The scientists do not come to the definitive conclusions yet. There are some aging theories as the following. The aging theories_part2 Error and repair The damaged cells will continue to rebuild and repair again and again in the entire life. Therefore repaired DNA only can recover 90% . The unrepaired of DNA function composed a lot of proteins will accumulate and cause the error messages transfer. This is reason of dysfunction and illness in the body. Caloric restriction Dr. Roy Walford in UCLA proposes “caloric restriction” theory. After long term animal experiments, he found caloric restricted animals are younger, good health, and have a long life compared to the without restricted ones. He thinks the reason of experiments results is caloric restriction can decrease weight to reach the saturation point and optimize the me...

Why do we get old? Can we live longer? Why do human age? Some elders are still healthy, but some are weak and sick. The scientists do not come to the definitive conclusions yet. There are some aging theories as the following.   The aging theories_part1 Wear and tear The cells wear and tear day and night and cause the function decline of organs like the tire wears. For example, the degenerative arthritis is because of cartilage worn.   Waste accumulation As time goes by, the cells will leave toxins and garbage after sickness in the body. These toxins and garbage will affect the metabolism of the body. For example, the lipofuscin and melisma is.     Immune suppression The young people are seldom sick, but the elders are easy to suffer from illness, even the cancer. Why? The phenomena may be  the immune system declining. Thymus gland is the primary lymph organ in our body and in charge of the function of immune system. When the ...

Tips to Soothe Sunburn Tip no. 1 Sunburn does not need to apply any skin care products. Long stay at home. Skin is not only redness with stinging but also burning sensation that is acute sunburn. At this moment, the skin is very sensitive and should deactivate any skin care products. Consult a doctor to seek proper medical treatment Tip no. 2 Sedative effect of the product should be noted ingredients inside. After sunburn, the products such as aloe vera gel or loofah water can make skin soothing cool. It should be noted whether there are other ingredient additives. Take note that sensitive skin is allergic to the products. Tip no. 3 Sunburn may be the cause of Rosacea. Sunburn of the skin is reddish and inflated. One of the reasons is the symptom of Rosacea. The skin gets to be reddish if exposed to sunshine. Immediate consultation from a physician is adviced. Tip no. 4 We need at least two kinds of skin care products due the season. Skin manifestations can ...